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Perioperative Nurse Career Overview

Written by: North Carolina Central University   •  Feb 1, 2024

A masked nurse wearing PPE assists in an operating room.

Nurses play a vital role in supporting patient outcomes throughout their clinical journeys. This includes promoting patient health, comfort, and safety for patients having surgery. The role of the perioperative nurse is to care for a patient before, during, and after they have an operation, to help ensure the best outcome and the fastest possible recovery.

For those who are drawn to the nursing profession and who gravitate toward the fast-paced nature of the operating room (OR), the perioperative role may be highly rewarding. An undergraduate degree in nursing can provide the foundational skills nurses need for long-lasting and impactful careers.

What’s a Perioperative Nurse?

Perioperative registered nurses (RNs), also known as scrub nurses or OR nurses, play an essential role in supporting the surgical team and ensuring ideal patient outcomes. The role of a perioperative nurse is based in the OR. Nurses who work in this position are present during operations, assisting surgeons and monitoring patients’ vital signs to ensure their comfort and safety.

What Does a Perioperative Nurse Do?

The roles and responsibilities associated with this position can vary from one job to the next. A typical job description looks something like this:

  • Working with patients to complete intake forms and other preliminary paperwork

  • Sterilizing ORs and surgical instruments

  • Addressing last-minute questions from patients before procedures

  • Monitoring patients’ vital signs during operations

  • Listening to directions from the surgeons and passing them instruments as needed

  • Verifying patients’ safety during procedures

  • Providing patients with postoperative instructions and recovery guidelines

Common Work Settings for Perioperative Nurses

The most common work environment for perioperative nurses is the hospital. In this setting, they may work in operating rooms, preoperative holding areas, or post-anesthesia care units (PACUs), supporting patients through every phase of surgery. Hospitals often offer opportunities to work with complex cases, advanced technology, and multidisciplinary surgical teams.

Perioperative nurses are also frequently employed in:

  • Ambulatory or outpatient surgery centers, which focus on same-day procedures

  • Specialty surgical hospitals, such as orthopedic or cardiac centers

  • Physician-owned surgical practices and clinics

  • Trauma centers where emergency surgeries are performed

  • Military or government health care facilities

Perioperative Nurse Responsibilities by Surgical Phase

Perioperative nurses play a vital role throughout the surgical experience, supporting patients before, during, and after procedures. Their responsibilities are often divided into three phases: preoperative, intraoperative, and postoperative care.

During the preoperative phase, perioperative nurses prepare patients physically and emotionally for surgery. This includes reviewing medical histories, verifying consent forms, checking vital signs, and preparing surgical sites and equipment.

In the intraoperative phase, nurses work in operating rooms as part of the surgical team. They maintain sterile environments, assist surgeons, handle instruments, monitor patients’ conditions, and ensure safety protocols are followed throughout procedures.

In the postoperative phase, nurses monitor patients as they recover from anesthesia and surgery. They assess vital signs, manage pain, watch for complications, and provide instructions for recovery. 

What’s the Typical Perioperative Nurse Salary?

The median annual salary for perioperative nurses was approximately $85,220 in December 2025, according to data from Payscale. Workers with salaries in the lowest 10% of the salary range made approximately $64,000, while those in the highest 10% made more than $125,000.

How to Become a Perioperative Nurse

To succeed in the role, cultivating the right set of clinical competencies and patient care skills is critical. The best way to do so is through diligent academic study, combined with on-site experience.

1. Earn a Degree

Before taking on any kind of nursing profession, it is essential to obtain an undergraduate degree in nursing. Coupled with this degree, one must develop the foundational skills needed to care for patients and interface with physicians. Some individuals earn a two-year associate degree, but employers generally prefer a four-year Bachelor of Science in Nursing (BSN).

2. Pass Exams

After completing a degree program, graduates can sit for the National Council Licensure Examination for Registered Nurses (NCLEX-RN), administered by the local nursing board. A passing score allows aspiring nurses to apply for licensure, become RNs, and begin practicing.

3. Gain Work Experience

The next step in the perioperative nurse career path is to gain experience assisting physicians, collaborating with other nurses, and tending to patients. Nursing shifts that allow for time in the OR or the intensive care unit (ICU) give individuals valuable experience that can translate into more permanent roles in the perioperative position.

4. Seek Certification

Usually, the most in-demand perioperative jobs go to nurses who are appropriately certified. A credential such as the Certified Perioperative Nurse (CNOR), offered by the Competency & Credentialing Institute (CCI), is available for those who have a couple of years of nursing experience, including some OR training.

5. Cultivate Skills

Through this balance of education and experience, nurses can hone the skills needed for perioperative success. Some particular skills to focus on include the following:

  • Critical thinking

  • Problem-solving

  • Verbal communication

  • Physical and emotional stamina

Pursue a Career in the Operating Room

Working as a perioperative nurse is a richly rewarding opportunity to support surgeons, provide high-impact patient care, and participate every day in a fast-paced and stimulating environment.

To prepare for a meaningful career in perioperative nursing, consider an online degree that focuses on vital nursing skills. NCCU Online’s online RN to BSN program is designed to help nurses develop broad skills that translate into clinical care environments.

Find out how NCCU Online can help you earn your spot in the operating room.

Recommended Readings

Nursing Career Path Steps: How to Advance From ADN to MSN (and Beyond)

Dr. Yolanda VanRiel: A Nurse Educator’s Journey of Purpose, Practice, and Pride

Hospice Nurse Career Overview

Sources:

Competency & Credentialing Institute, Certified Perioperative Nurse

Indeed, Perioperative Nursing: Definition, Duties and Career Path

Payscale, Average Registered Nurse (RN), Operating Room Hourly Pay

ZipRecruiter, What Is a Perioperative Nurse and How to Become One